一、基本信息

曹宇，副教授，硕士生导师，省级人才

研究领域：纳米药物的研发与应用，脑胶质瘤的精准诊断与治疗

电子邮件：caoyu@hubu.edu.cn

二、教育背景及工作经历

2022.11至今，湖北大学，健康科学与工程学院，副教授

2020-11至2022-10，湖北大学，化学化工学院，副教授

2019-07至2020-10，湖北大学，化学化工学院，讲师

2014-09至2019-06，北京科技大学，化学与生物工程学院，博士

2010-09至2014-06，北京科技大学，化学与生物工程学院，学士

三、研究方向

纳米药物的研发与应用，脑胶质瘤的精准诊断与治疗

四、科研项目

1. 国家自然科学基金青年项目，仿生MXene基二维声敏剂的构建及其脑胶质瘤声动力学治疗应用研究，2023/01-2025/12，30万，主持，在研。

2. 湖北省自然科学基金面上类项目，响应型仿生纳米药物的构建及其在脑胶质瘤声动力学治疗中的应用， 2021/10-2023/09，8万，主持，在研。

   五、代表性论文

   1.  Wu, T.; Liu, Y.; Cao, Y.^*; Liu, Z.^*, Engineering macrophage exosome disguised biodegradable nanoplatform for enhanced sonodynamic therapy of glioblastoma. Adv. Mater. 2022, e2110364.

   2.  Lu, H.; Guo, K.; Cao, Y.^*; Yang, F.; Wang, D.; Dou, L.^*; Liu, Y.^*; Dong, H.^*, Cancer cell membrane vesicle for multiplex microRNA imaging in living cells. Anal. Chem. 2020, 92, 1850-1855.

   3.  Cao, Y.; Wu, T.; Dai, W.; Dong, H.^*; Zhang, X.^*, TiO₂ Nanosheets with the Au Nanocrystal-Decorated Edge for Mitochondria-Targeting Enhanced Sonodynamic Therapy. Chemistry of Materials 2019, 31 (21), 9105-9114.

   4.  Cao, Y.; Wu, T.; Zhang, K.; Meng, X.; Dai, W.; Wang, D.; Dong, H.^*; Zhang, X.^*, Engineered Exosome-Mediated Near-Infrared-II Region V₂C Quantum Dot Delivery for Nucleus-Target Low-Temperature Photothermal Therapy. ACS Nano 2019, 13, 1499-510.

   5.  Cao, Y.; Li, S.; Chen, C.; Wang, D.; Wu, T.; Dong, H.^*; Zhang, X.^*, Rattle-type Au@Cu_2-xS hollow mesoporous nanocrystals with enhanced photothermal efficiency for intracellular oncogenic microRNA detection and chemo-photothermal therapy. Biomaterials 2018, 158, 23-33.

   6.  Cao, Y.; Meng, X.; Wang, D.; Zhang, K.; Dai, W.; Dong, H.^*; Zhang, X.^*, Intelligent MnO₂/Cu_2-xS for Multimode Imaging Diagnostic and Advanced Single-Laser Irradiated Photothermal/Photodynamic Therapy. ACS Appl. Mater. Interfaces 2018, 10, 17732-17741.

   7.  Cao, Y.; Dong, H.^*; Yang, Z.; Zhong, X.; Chen, Y.; Dai, W.; Zhang, X.^*, Aptamer-Conjugated Graphene Quantum Dots/Porphyrin Derivative Theranostic Agent for Intracellular Cancer-Related MicroRNA Detection and Fluorescence-Guided Photothermal/Photodynamic Synergetic Therapy. ACS Appl. Mater. Interfaces 2017, 9, 159-166.

   8.  Cao, Y.; Dong, H.^*; Pu, S.; Zhang, X.^*, Photoluminescent two-dimensional SiC quantum dots for cellular imaging and transport. Nano Research 2018, 11, 4074-4081.

审核人：吴康兵